Peptides · CAS 616204-22-9
Argireline
INCI: Acetyl Hexapeptide-8
Argireline is the expression-line peptide — a peptides cosmetic ingredient (Acetyl Hexapeptide-8, CAS 616204-22-9) supplied by RAWESS with a batch certificate of analysis on every lot. Key specification: Purity (HPLC) ≥ 99.0%. Minimum order quantity is 1 kg with a 10-14 days (synthesis slot) lead time; shipment is FOB · CIF · DDP from In-house SPPS · GMP suite. Typical use levels: Expression-line serums 3-10% · Targeted eye masks · Neck-firming formulas. Certification: ISO 22716 GMP · ISO 9001 · REACH registration support · vegan. Standard packaging: 1kg foil bag, cold chain; storage 2-8°C; shelf life 24 months, 2-8°C.
| INCI name | Acetyl Hexapeptide-8 |
|---|---|
| CAS number | 616204-22-9 |
| Product family | Peptides |
| Appearance | White lyophilized powder |
| Purity (HPLC) | ≥ 99.0% |
| MOQ | 1 kg |
| Lead time | 10-14 days (synthesis slot) |
| Packaging | 1kg foil bag, cold chain |
| Storage | 2-8°C |
| Origin | In-house SPPS · GMP suite |
| HS code | HS 2934.99 |
| Applications | Expression-line serums 3-10% · Targeted eye masks · Neck-firming formulas |
| Shelf life | 24 months, 2-8°C |
Why this grade
Acetyl hexapeptide-8 remains the reference ingredient for expression-line relaxation claims — but only at honest purity. We synthesize in-house on published batch slots: 99% by HPLC, delivered as the acetate salt in water-soluble lyophilized form.
Every lot carries MS sequence confirmation and residual counter-ion data. Use at 3-10% in aqueous serums and masks; stable in standard preservative systems. We share our in-vitro SNAP-25 assay dossier under NDA.
Key benefits
- 99% purity by HPLC with MS sequence confirmation
- Published synthesis slots — capacity you can plan production around
- Water-soluble lyophilized powder, no solvent carriers
- In-vitro efficacy dossier available under NDA
Technical specification
Ingredient profile
Acetyl Hexapeptide-8 is the classic expression-line peptide: a short, palmitoylated chain engineered to sit at the surface and soften mimic-muscle contractions over weeks of use. Our material is made by in-house solid-phase peptide synthesis (SPPS) in a GMP suite, so every batch carries the same sequence, the same 99%-plus purity by HPLC, and mass-spectrometry identity confirmation that would be hard to fake on paper.
Because it is sequence-defined rather than extract-defined, hexapeptide-8 offers formulators a reproducible alternative to neuro-mimetic actives. It is typically dosed at 0.5–2% in anhydrous or low-water serums and eye creams, where its thermal and pH stability window is widest.
The peptide is vegan, free of animal-derived starting materials, and covered by our REACH-aligned regulatory dossier for EU import. Common pairings include niacinamide for barrier support and low-molecular-weight hyaluronic acid for immediate plumping while the peptide builds its long-term effect.
Related: EU REACH 2026 peptide importer briefing · full catalog · request a sample
B2B supply terms
Applications
Sample & quote
100g evaluation sample with mini-COA ships within 48 hours for qualified buyers. Volume quote with tier pricing returns in one business day — with the batch COA attached, not promised.
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